喷雾干燥条件对骨痹颗粒复方水提液喷干粉吸湿性能的影响及其机制研究(4)
2. Key Laboratory of Chinese Herbal Compound Separation，Nanjing 210023，China)
[Abstract] Objective： To investigate moisture content and hygroscopicity of spray dry powder of Gubi compound′s water extract obtained at different spray drying conditions and laying a foundation for spray drying process of chinese herbal compound preparation.Method： In the paper，on the basis of single-factor experiments，the author choose inlet temperature，liquid density，feed rate，air flow rate as investigated factors.Result： The experimental absorption rate-time curve and scanning electron microscopy results showed that under different spray drying conditions the spray-dried powders have different morphology and different adsorption process. Conclusion： At different spray-dried conditions，the morphology and water content of the powder is different，these differences lead to differences in the adsorption process，at the appropriate inlet temperature and feed rate with a higher sample density and lower air flow rate，in the experimental system the optimum conditions is inlet temperature of 150 ℃，feed density of 1.05 g·mL-1，feed rate of 20 mL·min-1，air flow rate of 30 m3·h-1.
[Key words] spray drying conditions；hygroscopic；moisture；absorption rate-time curve；hygroscopic speed
doi：10.4268/cjcmm20140422, http://www.100md.com(宗杰 邵琪 张红芹 潘永兰 朱华旭 郭立玮)
[Abstract] Objective： To investigate moisture content and hygroscopicity of spray dry powder of Gubi compound′s water extract obtained at different spray drying conditions and laying a foundation for spray drying process of chinese herbal compound preparation.Method： In the paper，on the basis of single-factor experiments，the author choose inlet temperature，liquid density，feed rate，air flow rate as investigated factors.Result： The experimental absorption rate-time curve and scanning electron microscopy results showed that under different spray drying conditions the spray-dried powders have different morphology and different adsorption process. Conclusion： At different spray-dried conditions，the morphology and water content of the powder is different，these differences lead to differences in the adsorption process，at the appropriate inlet temperature and feed rate with a higher sample density and lower air flow rate，in the experimental system the optimum conditions is inlet temperature of 150 ℃，feed density of 1.05 g·mL-1，feed rate of 20 mL·min-1，air flow rate of 30 m3·h-1.
[Key words] spray drying conditions；hygroscopic；moisture；absorption rate-time curve；hygroscopic speed
doi：10.4268/cjcmm20140422, http://www.100md.com(宗杰 邵琪 张红芹 潘永兰 朱华旭 郭立玮)