基于药物生物效应的中药寒热属性分类研究策略(5)
A cold/heat property classification strategy based on
bio-effects of herbal medicines
JIANG Miao， LV Ai-ping
(Institute of Basic Research In Clinical Medicine， China Academy of Traditional Chinese Medicine， Beijing 100700， China)
[Abstract] The property theory of Chinese herbal medicine (CHM) is regarded as the core and basic of Chinese medical theory， however， the underlying mechanism of the properties in CHMs remains unclear， which impedes a barrier for the modernization of Chinese herbal medicine. The properties of CHM are often categorized into cold and heat according to the theory of Chinese medicine， which are essential to guide the clinical application of CHMs. There is an urgent demand to build a cold/heat property classification model to facilitate the property theory of Chinese herbal medicine， as well as to clarify the controversial properties of some herbs. Based on previous studies on the cold/heat properties of CHM， in this paper， we described a novel strategy on building a cold/heat property classification model based on herbal bio-effect. The interdisciplinary cooperation of systems biology， pharmacological network， and pattern recognition technique might lighten the study on cold/heat property theory， provide a scientific model for determination the cold/heat property of herbal medicines， and a new strategy for expanding the Chinese herbal medicine resources as well.
[Key words] herbal properties； cold/heat property； biological effect； pharmacological network； pattern recognition
doi：10.4268/cjcmm20141141
[责任编辑 张宁宁], 百拇医药(姜淼 吕爱平)
bio-effects of herbal medicines
JIANG Miao， LV Ai-ping
(Institute of Basic Research In Clinical Medicine， China Academy of Traditional Chinese Medicine， Beijing 100700， China)
[Abstract] The property theory of Chinese herbal medicine (CHM) is regarded as the core and basic of Chinese medical theory， however， the underlying mechanism of the properties in CHMs remains unclear， which impedes a barrier for the modernization of Chinese herbal medicine. The properties of CHM are often categorized into cold and heat according to the theory of Chinese medicine， which are essential to guide the clinical application of CHMs. There is an urgent demand to build a cold/heat property classification model to facilitate the property theory of Chinese herbal medicine， as well as to clarify the controversial properties of some herbs. Based on previous studies on the cold/heat properties of CHM， in this paper， we described a novel strategy on building a cold/heat property classification model based on herbal bio-effect. The interdisciplinary cooperation of systems biology， pharmacological network， and pattern recognition technique might lighten the study on cold/heat property theory， provide a scientific model for determination the cold/heat property of herbal medicines， and a new strategy for expanding the Chinese herbal medicine resources as well.
[Key words] herbal properties； cold/heat property； biological effect； pharmacological network； pattern recognition
doi：10.4268/cjcmm20141141
[责任编辑 张宁宁], 百拇医药(姜淼 吕爱平)