短波理疗联合强脉冲光治疗面部糖皮质激素依赖性皮炎临床观察(1)
[摘要]目的：观察短波理疗联合强脉冲光治疗面部糖皮质激素依赖性皮炎的临床疗效及安全性。方法：将120例患者随机分为三组。短波理疗联合强脉冲光治疗组：40例；对照1组(短波理疗组)：40例；对照2组(强脉冲光组)：40例。治疗3个月后比较三组临床疗效，并随访1月后复发情况。结果：治疗3个月后，治疗组、对照1组及对照2组有效率分别为87.20%、60.0%、66.70%，治疗组有效率显著高于对照1组与对照2组，差异有统计学意义(P<0.05)，对照1组与对照2组有效率比较，差异无统计学意义(P>0.05)。1个月后治疗组、对照1组、对照2组复发率分别为3.33%、6.67%、13.33%，治疗过程中均未出现严重不良反应。结论：短波理疗联合强脉冲光治疗面部糖皮质激素依赖性皮炎疗效确切，值得推广。
[关键词] 短波理疗；强脉冲光；面部；糖皮质激素依赖性皮炎；不良反应；复发
[中图分类号]R758.22 [文献标志码]A [文章编号]1008-6455(2018)11-0036-03
, 百拇医药
Abstract： Objective To observe the clinical efficacy of Desensitization apparatus Combined with Intense pulsed light in the treatment of facial glucocorticosteroid-dependent dermatitis. Methods One hundred and twenty patients with facial glucocorticosteroid-dependent dermatitis were randomly divided into three groups. Treatment group (40 cases) treated with Desensitization apparatus combined with Intense pulsed light， the control group one (40 cases) treated only with Desensitization apparatus and the control group two (40 cases) treated only with Intense pulsed light. The clinical efficacy and safety were assessed 3 months after treatment. Meanwhile， recurrences were assessed one month later. Results The effective rate of treatment group was 87.20%， which was higher than those in the control group one and the control group two(60.00% and 66.70%). The recurrence rate in the treatment group，the control group one and the control group two was respectively 3.33%， 6.67% and 13.33%. No serious adverse reactions were found in the three groups. Conclusion The desensitization apparatus combined with Intense pulsed light is effective and less recurrence in the treatment of facial glucocorticosteroid-dependent dermatitis. Moreover，it is worthy of wide application in clinical.
, 百拇医药
Key words： desensitization apparatus；intense pulse light；face；corticosteroid-depengdent；adverse reactions；recurrence
近年来，网购、微商盛行，各种渠道售卖不合格护肤品比例上升，其中非法添加糖皮质激素制剂，导致面部激素依赖性皮炎发病率不断上升。临床表现主要为面部毛细血管扩张、脱屑、瘙痒、潮红等，给患者生活、社交带来困扰，心理造成极大痛苦，甚至出现严重焦虑、忧郁等心理问题[1-2]。目前针对糖皮质激素依赖性皮炎的治疗包括：修复皮肤屏障功能、抗感染、抗炎及心理治療等[3]，但仍无有效而快速的治疗方式，笔者科室尝试短波理疗联合强脉冲光治疗面部糖皮质激素依赖性皮炎取得了满意疗效，现将结果报道如下。
1 资料和方法
1.1 一般资料：选择2017年1月-2017年12月于笔者科室门诊就诊的120例面部糖皮质激素依赖性皮炎患者。按照随机数字表法分为三组。治疗组：40例，短波理疗联合强脉冲光治疗；对照1组：40例，仅采用短波理疗；对照2组：40例，仅采用强脉冲光治疗。三组患者的一般情况比较，差异均无统计学意义(P>0.05)，见表1。
1.2 纳入标准：①符合面部糖皮质激素依赖性皮炎的临床诊断标准[4]；②年龄18～60岁，性别不限；③患者知情同意，自愿参加本研究并签署知情同意书及照片使用协议；④能坚持配合治疗和疗效观察。
1.3 排除标准：①存在严重光过敏病史及半年内服用过光敏性药物者；②重要脏器严重功能不全者；③妊娠期、哺乳期女性；④病例资料不全者。治疗过程中治疗组与对照2组分别有1例患者不能耐受强脉冲光治疗退出治疗。, http://www.100md.com(文丽萍 周书帆 邓映)
[关键词] 短波理疗；强脉冲光；面部；糖皮质激素依赖性皮炎；不良反应；复发
[中图分类号]R758.22 [文献标志码]A [文章编号]1008-6455(2018)11-0036-03
, 百拇医药
Abstract： Objective To observe the clinical efficacy of Desensitization apparatus Combined with Intense pulsed light in the treatment of facial glucocorticosteroid-dependent dermatitis. Methods One hundred and twenty patients with facial glucocorticosteroid-dependent dermatitis were randomly divided into three groups. Treatment group (40 cases) treated with Desensitization apparatus combined with Intense pulsed light， the control group one (40 cases) treated only with Desensitization apparatus and the control group two (40 cases) treated only with Intense pulsed light. The clinical efficacy and safety were assessed 3 months after treatment. Meanwhile， recurrences were assessed one month later. Results The effective rate of treatment group was 87.20%， which was higher than those in the control group one and the control group two(60.00% and 66.70%). The recurrence rate in the treatment group，the control group one and the control group two was respectively 3.33%， 6.67% and 13.33%. No serious adverse reactions were found in the three groups. Conclusion The desensitization apparatus combined with Intense pulsed light is effective and less recurrence in the treatment of facial glucocorticosteroid-dependent dermatitis. Moreover，it is worthy of wide application in clinical.
, 百拇医药
Key words： desensitization apparatus；intense pulse light；face；corticosteroid-depengdent；adverse reactions；recurrence
近年来，网购、微商盛行，各种渠道售卖不合格护肤品比例上升，其中非法添加糖皮质激素制剂，导致面部激素依赖性皮炎发病率不断上升。临床表现主要为面部毛细血管扩张、脱屑、瘙痒、潮红等，给患者生活、社交带来困扰，心理造成极大痛苦，甚至出现严重焦虑、忧郁等心理问题[1-2]。目前针对糖皮质激素依赖性皮炎的治疗包括：修复皮肤屏障功能、抗感染、抗炎及心理治療等[3]，但仍无有效而快速的治疗方式，笔者科室尝试短波理疗联合强脉冲光治疗面部糖皮质激素依赖性皮炎取得了满意疗效，现将结果报道如下。
1 资料和方法
1.1 一般资料：选择2017年1月-2017年12月于笔者科室门诊就诊的120例面部糖皮质激素依赖性皮炎患者。按照随机数字表法分为三组。治疗组：40例，短波理疗联合强脉冲光治疗；对照1组：40例，仅采用短波理疗；对照2组：40例，仅采用强脉冲光治疗。三组患者的一般情况比较，差异均无统计学意义(P>0.05)，见表1。
1.2 纳入标准：①符合面部糖皮质激素依赖性皮炎的临床诊断标准[4]；②年龄18～60岁，性别不限；③患者知情同意，自愿参加本研究并签署知情同意书及照片使用协议；④能坚持配合治疗和疗效观察。
1.3 排除标准：①存在严重光过敏病史及半年内服用过光敏性药物者；②重要脏器严重功能不全者；③妊娠期、哺乳期女性；④病例资料不全者。治疗过程中治疗组与对照2组分别有1例患者不能耐受强脉冲光治疗退出治疗。, http://www.100md.com(文丽萍 周书帆 邓映)
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