传统气功疗法对慢性阻塞性肺疾病患者抑郁、焦虑评分影响的系统评价(1)
摘要 目的：评价传统气功疗法降低慢性阻塞性肺疾病患者抑郁评分、焦虑评分的临床疗效及安全性。方法：检索中国知网数据库(CNKI，1979—2017)、万方数据库(Wanfang Data，1998—2017)、重庆维普中文科技期刊数据库(VIP，1979—2017)、中国生物医学文献数据库(Sino Med，1978—2017)、Pub Med(1966_2017)及Cochrane图书馆，截止时间2017年3月31日，收集所有以气功为主要干预措施治疗慢性阻塞性肺疾病患者焦虑评分、抑郁评分的随机对照试验。两名研究者分别进行资料提取和严格评价，使用Rev Man5.3进行Meta分析。结果：纳入7项随机对照研究，485例患者。Meta分析显示，相对于单纯常规治疗或不治疗，气功结合常规治疗能明显改善患者抑郁评分(SMD-0.79，95%CI-1.09～-0.49，P<0.001，I =60%)、焦虑评分(SMD-0.73，95%CI-0.97～-0.49，P<0.001，I =39%)、6 min步行试验(MD 24.3，95% CI 13.83～34.77，P=0.006，I =66%)距离、日常生活评分(MD-2.23，95% CI-2.90～-1.56，P=0.26，I =25%)。结论：气功疗法可能对改善慢性阻塞性肺疾病患者焦虑评分、抑郁评分具有一定益处，对改善患者日常生命质量等方面具有辅助作用。
关键词 慢性阻塞性肺疾病；抑郁；焦虑；随机对照试验；气功；太极；六字诀；五禽戏
Abstract Objective：To investigate the clinical efficacy and safety of traditional Qigong therapy on depression and anxiety score in patients with chronic obstructive pulmonary disease (COPD).Methods：Data in China National Knowledge Infrastructure (CNKI，1979-2017)，Wanfang database (Wanfang Data，1998-2017)，Chongqing VIP Chinese scientific journal database (VIP，1979-2017)，Chinese biomedical literature database (Sino Med，1978-2017)，PubMed (1966-2017)，and Cochrane Library before March 31，2017 were searched.Randomized controlled trials (RCTs) by taking Qigong as the main treatment for depression and anxiety score in patients with COPD were collected.Two researchers independently screened the literature and extract data.The included literature was assessed by Cochrane bias risk and analyzed by RevMan 5.3.Results：A total of 7 RCTs involving 485 patients were included.Meta-analysis showed that，compared with conventional treatment alone or no treatment，qigong combined with routine treatment could significantly improve depression score of patients (SMD -0.79，95%CI -1.09 to -0.49，P<0.001，I =60%)，the score of anxiety (SMD -0.73，95%CI -0.97 to -0.49，P<0.001，I =39%)，six minutes′ walk test distance (MD 24.3，95% CI from 13.83 to 34.77，P=0.006，I =66%)，daily life score (MD -2.23，95% CI -2.90 to -1.56，P=0.26，I =25%).Conclusion：Qigong may have certain benefits for anxiety and depression score of patients with COPD.At the same time，it may have auxiliary effects on improving the quality of daily life of patients.
Key Words COPD； Depression； Anxiety； RCT； Qigong； Taichi； Liuzijue Qigong； Wuqinxi
中圖分类号：R247；R563文献标识码：Adoi：10.3969/j.issn.1673-7202.2018.04.052
合并症的存在严重影响着慢性阻塞性肺疾病(Chronic Obstructive Pulmonary Disease，COPD)的发生发展[1]。焦虑、抑郁是COPD的常见合并症之一，其发生机制可能与生理、心理和社会等多种因素有关。患者长期呼吸困难、咳嗽、咯痰，随着肺功能逐年下降，生命质量受到严重影响，逐步出现烦躁、情绪低落、焦虑抑郁等情绪。这些负面情绪又影响着原发病的发生、发展，使得急性加重次数增多，生命质量进一步下降，引起极大的社会和经济负担。, http://www.100md.com(吴建军 刘金民 崔红生 孙博 姜良铎)
关键词 慢性阻塞性肺疾病；抑郁；焦虑；随机对照试验；气功；太极；六字诀；五禽戏
Abstract Objective：To investigate the clinical efficacy and safety of traditional Qigong therapy on depression and anxiety score in patients with chronic obstructive pulmonary disease (COPD).Methods：Data in China National Knowledge Infrastructure (CNKI，1979-2017)，Wanfang database (Wanfang Data，1998-2017)，Chongqing VIP Chinese scientific journal database (VIP，1979-2017)，Chinese biomedical literature database (Sino Med，1978-2017)，PubMed (1966-2017)，and Cochrane Library before March 31，2017 were searched.Randomized controlled trials (RCTs) by taking Qigong as the main treatment for depression and anxiety score in patients with COPD were collected.Two researchers independently screened the literature and extract data.The included literature was assessed by Cochrane bias risk and analyzed by RevMan 5.3.Results：A total of 7 RCTs involving 485 patients were included.Meta-analysis showed that，compared with conventional treatment alone or no treatment，qigong combined with routine treatment could significantly improve depression score of patients (SMD -0.79，95%CI -1.09 to -0.49，P<0.001，I =60%)，the score of anxiety (SMD -0.73，95%CI -0.97 to -0.49，P<0.001，I =39%)，six minutes′ walk test distance (MD 24.3，95% CI from 13.83 to 34.77，P=0.006，I =66%)，daily life score (MD -2.23，95% CI -2.90 to -1.56，P=0.26，I =25%).Conclusion：Qigong may have certain benefits for anxiety and depression score of patients with COPD.At the same time，it may have auxiliary effects on improving the quality of daily life of patients.
Key Words COPD； Depression； Anxiety； RCT； Qigong； Taichi； Liuzijue Qigong； Wuqinxi
中圖分类号：R247；R563文献标识码：Adoi：10.3969/j.issn.1673-7202.2018.04.052
合并症的存在严重影响着慢性阻塞性肺疾病(Chronic Obstructive Pulmonary Disease，COPD)的发生发展[1]。焦虑、抑郁是COPD的常见合并症之一，其发生机制可能与生理、心理和社会等多种因素有关。患者长期呼吸困难、咳嗽、咯痰，随着肺功能逐年下降，生命质量受到严重影响，逐步出现烦躁、情绪低落、焦虑抑郁等情绪。这些负面情绪又影响着原发病的发生、发展，使得急性加重次数增多，生命质量进一步下降，引起极大的社会和经济负担。, http://www.100md.com(吴建军 刘金民 崔红生 孙博 姜良铎)
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