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薄型子宫内膜30例临床分析(2)
http://www.100md.com 2013年1月25日 关少艮
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    参见附件。

     总而然之,上述的治疗方法都是试图通过增加体内雌激素、改善子宫、卵巢血流供应,促进子宫腺体及血管增生,增加子宫内膜雌、孕激素受体数量等途径来改善子宫内膜厚度及容受性[15]。但目前这些干预措施的临床效果仍欠确切。这些方法的尝试均有一定的疗效但仍有相当部分的病例对上述治疗无反应,同时也需要大样本的随机对照研究提供循证医学证据。

    本文对子宫内膜的容受性检测仅限于子宫内膜的测量,存在着一定的局限性,在今后的研究中应增加子宫内膜形态和血流的监测,以及子宫内膜分子生物学相关的检测,并增加样本量减少个体误差,以寻求更有效治疗薄型子宫内膜的方法。

    参 考 文 献

    [1] Senturk LM, Erel CT. Thin endometrium in assisted reproductive technology. Curr Opin Obstet Gynecol,2008, 20(3):221-8.

    [2] Schild RL, Knobloch C, Dorn C, et al. Endometrial receptivity in an in vitro fertilization program as assessed by spiral artery blood flow, endometrial thickness, endometrial volume, and uterine artery blood flow. Fertil Steril, 2001, 75(2):361-6.Senturk LM, Erel CT. Thin endometrium in assisted reproductive technology. Curr Opin Obstet Gynecol,2008, 20(3):221-8.

    [3] de Geyter C, Schmitter M, de Geyter M, et al. Prospective evaluation of the ultrasound appearance of the endometrium in a cohort of 1 186 infertile women. Fertil Steril, 2000, 73(1):106-13.

    [4] Zhang X, Chen CH, Confino E, et al. Increased endometrial thickness is associated with improved treatment outcome for selected patients undergoing in vitro fertilization embryo transfer. Fertil Steril, 2005, 83(2):336-40.

    [5] 杨海虹, 叶碧绿, 吕杰强, 等. 氯米芬合用阿司匹林对子宫内膜发育和子宫血流的影响. 实用妇产科杂志, 2005,-53-21(2):114-5.

    [6] Zinger M, Liu JH, Thomas MA. Successful use of vaginal sildenafil citrate in two infertility patients with Ashermans syndrome. J Womens Health(Larchmt), 2006, 15(4):442-4.

    [7] Ledee-Bataille N, Olivennes F, Lefaix JL, et al. Combined treatment by pentoxifylline and tocopherol for recipient women with a thin endometrium enrolled in an oocyte donation programme ......

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