【摘要】 目的 观察帕洛诺司琼联合地塞米松预防腹腔镜胆囊切除术后恶心呕吐(PONV)的效果。方法 120 例择期行腹腔镜胆囊切除术患者随机分为帕洛诺司琼组、地塞米松组、联合组， 每组40 例。观察手术后24 h内恶心呕吐发生率。结果 联合组术后恶心呕吐的发生率显著低于帕洛诺司琼组和地塞米松组， 差异有统计学意义(P<0.05)。结论 帕洛诺司琼联合地塞米松预防腹腔镜胆囊切除术后恶心呕吐较单药更为有效， 值得临床推广应用。

    【关键词】 帕洛诺司琼；地塞米松；腹腔镜胆囊切除术；术后恶心呕吐

    DOI：10.14163/j.cnki.11-5547/r.2015.24.014

    【Abstract】 Objective To observe effect by palonosetron combined with dexamethasone in prevention of postoperative nausea and vomiting (PONV) in laparoscopic cholecystectomy. Methods A total of 120 patients receiving laparoscopic cholecystectomy were randomly divided into palonosetron group ......