[摘要]目的 探讨左西孟坦联合血液净化治疗难治性心力衰竭的效果。方法 选取2015年7月～2017年2月在我院急诊ICU接受治疗的80例难治性心力衰竭患者作为研究对象，采用单双号随机分组的方式分为对照组与治疗组，各40例。对照组患者在常规心力衰竭药物的基础上加用多巴酚丁胺联合托拉塞米和(或)呋噻米进行治疗，治疗组患者在常规心力衰竭药物的基础上加用左西孟联合血液净化治疗，比较两组患者的总有效率、心室射血分数(LVEF)、每分钟心排指數(CI)、NT-proBNP变化。结果 治疗组的总有效率高于对照组，差异有统计学意义(P<0.05)。治疗组治疗后的NT-proBNP水平低于对照组，LVEF、CI水平高于对照组，差异有统计学意义(P<0.05)。结论 左西孟坦联合血液净化治疗难治性心力衰竭的疗效明显，值得在临床推广。

    [关键词]难治性心力衰竭；左西孟坦联合血液净化；疗效

    [中图分类号] R541.6 [文献标识码] A [文章编号] 1674-4721(2017)12(a)-0040-03

    [Abstract]Objective To explore the effect of Levosimendan associated with blood purification in the treatment of refractory heart failure.Methods 80 patients with refractory heart failure who were treated in EICU of our hospital from July 2015 to February 2017 were selected and divided into the control group and the treatment group according to the method of odd and even random grouping ......