不同方法治疗宫腔粘连的临床效果(1)
[摘要]目的 探討不同方法治疗宫腔粘连(IUA)的临床效果。方法 选取2013年1月～2016年12月在我院妇科治疗的105例IUA患者作为研究对象，按治疗方法分为三组，每组各35例。Ⅰ组接受宫腔镜下宫腔粘连分离术联合上环术治疗;Ⅱ组接受宫腔镜下宫腔粘连分离术联合COOK球囊扩张治疗14 d取出;Ⅲ组接受宫腔镜下宫腔粘连分离术联合COOK球囊扩张治疗7 d取出;三组均同时服用戊酸雌二醇联合地屈孕酮治疗3个月，3个月后复查。比较三组治疗前后子宫内膜增长，月经量变化，治疗效果，凝血功能相关指标及再粘连发生情况。结果 Ⅱ及Ⅲ组临床治疗总有效率明显高于Ⅰ组，差异有统计学意义(P<0.05)，但Ⅱ及Ⅲ组比较，差异无统计学意义(P>0.05);术前各组评分比较，差异无统计学意义(P>0.05)，Ⅱ及Ⅲ组的术后评分低于Ⅰ组，术后评分改善率高于Ⅰ组，差异均有统计学意义(P<0.05);Ⅱ及Ⅲ组月经好转率明显高于Ⅰ组(P<0.05)，但Ⅱ及Ⅲ组间比较，差异无统计学意义(P>0.05)。结论 宫腔镜下宫腔粘连分离术联合球囊扩张治疗IUA患者，可显著提高治疗效果，改善患者预后，临床优势明显。
[关键词]宫腔粘连;宫腔镜下宫腔粘连分离术;COOK球囊
[中图分类号] R711 [文献标识码] A [文章编号] 1674-4721(2019)2(a)-0137-03
[Abstract] Objective To study the clinical effect of different methods in the treatment of intrauterine adhesions (IUA). Methods A total of 105 cases of IUA treated in our hospital from January 2013 to December 2016 were selected and divided into 3 groups according to the treatment method， 35 cases in each group. The group Ⅰ received hysteroscopic adhesion separation combined with superior ring surgery. The group Ⅱ received hysteroscopic hysteroscopy combined with COOK balloon dilation for 14 days. The group Ⅲ was treated with hysteroscopic adhesions separation and COOK balloon dilation for 7 days. All the three groups were treated with Estradiol Valerate combined with Diproprogesterone for 3 months. Before and after treatment in the three groups with the endometrial growth， menstrual volume， therapeutic effect， coagulation function related indexes and the occurrence of re-adhesion were compared. Results The total effective rate of clinical treatment in group Ⅱand Ⅲ were significantly higher than that in group Ⅰ (P<0.05)， but there was no significant difference between group Ⅱand Ⅲ(P>0.05). There was no significant difference in the score of each group before operation (P>0.05). The postoperative scores of group Ⅱand Ⅲ were lower than that of group Ⅰ， and the improvement rate of postoperative score was higher than that of group Ⅰ (P<0. 05). The menstrual change rate of groupⅡand Ⅲ were significantly higher than that of group Ⅰ(P<0.05)， but there was no significant difference between group Ⅱand Ⅲ(P>0.05). Conclusion Hysteroscopy combined with balloon dilation in the treatment of IUA can significantly improve the therapeutic effect and improve the prognosis of patients with obvious clinical advantages.
[Key words] Intrauterine adhesion; Separation of intrauterine adhesions; COOK balloon, 百拇医药(海娜 郭天棋)
[关键词]宫腔粘连;宫腔镜下宫腔粘连分离术;COOK球囊
[中图分类号] R711 [文献标识码] A [文章编号] 1674-4721(2019)2(a)-0137-03
[Abstract] Objective To study the clinical effect of different methods in the treatment of intrauterine adhesions (IUA). Methods A total of 105 cases of IUA treated in our hospital from January 2013 to December 2016 were selected and divided into 3 groups according to the treatment method， 35 cases in each group. The group Ⅰ received hysteroscopic adhesion separation combined with superior ring surgery. The group Ⅱ received hysteroscopic hysteroscopy combined with COOK balloon dilation for 14 days. The group Ⅲ was treated with hysteroscopic adhesions separation and COOK balloon dilation for 7 days. All the three groups were treated with Estradiol Valerate combined with Diproprogesterone for 3 months. Before and after treatment in the three groups with the endometrial growth， menstrual volume， therapeutic effect， coagulation function related indexes and the occurrence of re-adhesion were compared. Results The total effective rate of clinical treatment in group Ⅱand Ⅲ were significantly higher than that in group Ⅰ (P<0.05)， but there was no significant difference between group Ⅱand Ⅲ(P>0.05). There was no significant difference in the score of each group before operation (P>0.05). The postoperative scores of group Ⅱand Ⅲ were lower than that of group Ⅰ， and the improvement rate of postoperative score was higher than that of group Ⅰ (P<0. 05). The menstrual change rate of groupⅡand Ⅲ were significantly higher than that of group Ⅰ(P<0.05)， but there was no significant difference between group Ⅱand Ⅲ(P>0.05). Conclusion Hysteroscopy combined with balloon dilation in the treatment of IUA can significantly improve the therapeutic effect and improve the prognosis of patients with obvious clinical advantages.
[Key words] Intrauterine adhesion; Separation of intrauterine adhesions; COOK balloon, 百拇医药(海娜 郭天棋)