血常规检查和血清铁蛋白检查在缺铁性贫血感染疾病中的诊断价值
[摘要]目的 探讨血常规检查和血清铁蛋白检查在缺铁性贫血感染疾病中的诊断价值。方法 选取2018年2月～2019年4月我院收治且疑似缺铁性贫血感染的患者68例作为研究对象，所有患者均接受血常规检查和血清铁蛋白检查。比较两种检查方法的灵敏度、特异性和准确率。结果 68例疑似缺铁性贫血感染的患者中，病理检查确诊为缺铁性贫血感染的患者50例，非缺铁性贫血感染的患者18例;血清铁蛋白检查缺铁性贫血感染的患者41例，阴性27例;血常规检查缺铁性贫血感染的患者46例，阴性22例。两种检查方法的灵敏度、特异性和准确率比较，差异无统计学意义(P>0.05)。结论 缺铁性贫血感染患者行血常规检查和血清铁蛋白检查，其灵敏度、特异性和准确率相当，临床应根据患者的实际情况选择检查方法。
[关键词]地中海贫血;缺铁性贫血;血常规;诊断价值
[中图分类号] R556.3 [文献标识码] A [文章编号] 1674-4721(2020)2(a)-0204-03
Diagnostic value of routine blood examination and serum ferritin examination in iron deficiency anemia infection
GUAN Xi-hua
Department of Clinical Laboratory， Anshan Cancer Hospital， Liaoning Province， Anshan 114033， China
[Abstract] Objective To explore the diagnostic value of routine blood examination and serum ferritin examination in iron deficiency anemia infection. Methods Sixty-eight patients suspected with iron deficiency anemia infection in our hospital from February 2018 to April 2019 were selected as the study objects， all patients received routine blood tests and serum ferritin tests. The sensitivity， specificity and accuracy of the two methods were compared. Results Among 68 patients suspected with iron deficiency anemia infection， 50 cases were diagnosed as iron deficiency anemia infection by pathological examination， and 18 cases were non iron deficiency anemia infection. 41 patients were diagnosed as iron deficiency anemia infection by serum ferritin， and 27 cases were detected in negative. 46 patients were diagnosed as iron deficiency anemia infection by blood routine examination， and 22 cases were detected in negative， there were no significant differences in sensitivity， specificity and accuracy between the two methods (P>0.05). Conclusion The sensitivity， specificity and accuracy of routine blood test and serum ferritin test in patients with iron deficiency anemia infection are similar. The clinical examination method should be selected according to the actual situation of patients.
[Key words] Thalassemia; Iron deficiency anemia; Routine blood; Diagnostic value
当人体对铁的需求以及供应失衡，将造成铁在体内清空，发生缺铁性贫血的疾病[1]，为贫血疾病中最常见的一种，临床可单独出现，也可伴随其他疾病发生。随着病情发展可见机体血红蛋白(Hb)发生缺陷，体内的红细胞生成受到感染，引起低色素性貧血。可靠的诊断方法是保证疾病治疗效果的关键所在，临床一般将Hb及血清铁蛋白电泳测定法对贫血进行鉴定，但上述方法的检查所需时间较长。国内外大量研究显示，血常规检测可快速诊断缺铁性贫血，有利于病症的诊断和后期诊治，其灵敏度、特异性以及准确性相对较高[2]，同时平均红细胞体积(MCV)和红细胞体积分布宽度(RDW)的异常变化，还可鉴别贫血类型，与地中海贫血相区别，便于下一步治疗方案的制订与顺利实施。缺铁性贫血与地中海贫血均为小细胞低色素性贫血，血常规检测具有操作简单、准确性高等优势。本研究旨在探讨血常规检查和血清铁蛋白检查在缺铁性贫血感染疾病中的诊断价值，现报道如下。, 百拇医药(关喜华)
[关键词]地中海贫血;缺铁性贫血;血常规;诊断价值
[中图分类号] R556.3 [文献标识码] A [文章编号] 1674-4721(2020)2(a)-0204-03
Diagnostic value of routine blood examination and serum ferritin examination in iron deficiency anemia infection
GUAN Xi-hua
Department of Clinical Laboratory， Anshan Cancer Hospital， Liaoning Province， Anshan 114033， China
[Abstract] Objective To explore the diagnostic value of routine blood examination and serum ferritin examination in iron deficiency anemia infection. Methods Sixty-eight patients suspected with iron deficiency anemia infection in our hospital from February 2018 to April 2019 were selected as the study objects， all patients received routine blood tests and serum ferritin tests. The sensitivity， specificity and accuracy of the two methods were compared. Results Among 68 patients suspected with iron deficiency anemia infection， 50 cases were diagnosed as iron deficiency anemia infection by pathological examination， and 18 cases were non iron deficiency anemia infection. 41 patients were diagnosed as iron deficiency anemia infection by serum ferritin， and 27 cases were detected in negative. 46 patients were diagnosed as iron deficiency anemia infection by blood routine examination， and 22 cases were detected in negative， there were no significant differences in sensitivity， specificity and accuracy between the two methods (P>0.05). Conclusion The sensitivity， specificity and accuracy of routine blood test and serum ferritin test in patients with iron deficiency anemia infection are similar. The clinical examination method should be selected according to the actual situation of patients.
[Key words] Thalassemia; Iron deficiency anemia; Routine blood; Diagnostic value
当人体对铁的需求以及供应失衡，将造成铁在体内清空，发生缺铁性贫血的疾病[1]，为贫血疾病中最常见的一种，临床可单独出现，也可伴随其他疾病发生。随着病情发展可见机体血红蛋白(Hb)发生缺陷，体内的红细胞生成受到感染，引起低色素性貧血。可靠的诊断方法是保证疾病治疗效果的关键所在，临床一般将Hb及血清铁蛋白电泳测定法对贫血进行鉴定，但上述方法的检查所需时间较长。国内外大量研究显示，血常规检测可快速诊断缺铁性贫血，有利于病症的诊断和后期诊治，其灵敏度、特异性以及准确性相对较高[2]，同时平均红细胞体积(MCV)和红细胞体积分布宽度(RDW)的异常变化，还可鉴别贫血类型，与地中海贫血相区别，便于下一步治疗方案的制订与顺利实施。缺铁性贫血与地中海贫血均为小细胞低色素性贫血，血常规检测具有操作简单、准确性高等优势。本研究旨在探讨血常规检查和血清铁蛋白检查在缺铁性贫血感染疾病中的诊断价值，现报道如下。, 百拇医药(关喜华)