开放性手术与腹腔镜术对结直肠癌患者术后并发症的不同风险因素研究(1)
【摘要】 目的：研究開放性手术与腹腔镜术对结直肠癌患者术后并发症的不同风险因素影响。方法：回顾性分析2017年1月-2020年1月在笔者所在医院进行手术治疗的96例结直肠癌患者的临床资料，按不同的治疗术式将其分为A组与B组，每组48例。A组采用开放性手术治疗，B组采用腹腔镜术治疗，统计两组术后并发症发生情况，并对导致并发症的风险因素进行分析。结果：A组术后并发症总发生率(47.92%)高于B组(27.08%)，A组术后感染、吻合口瘘发生率高于B组，差异均有统计学意义(P<0.05);多因素Logistic回归分析显示，年龄、输血量、出血量、手术时间、癌症TNM分期是A组术后发生并发症的相关因素(P<0.05)，年龄、腹部手术史、手术时间、癌症TNM分期是B组术后发生并发症的相关因素(P<0.05)。结论：腹腔镜手术术后并发症发生率较开放性手术低，其能够减少由于年龄、出血量及手术时间等因素而导致的术后并发症，术前加强对患者情况的评估，能够在很大程度上减少术后并发症。
【关键词】 开放性手术 腹腔镜术 结直肠癌 术后并发症 风险因素
doi：10.14033/j.cnki.cfmr.2020.27.021 文献标识码 B 文章编号 1674-6805(2020)27-00-04
[Abstract] Objective： To investigate the influence of open surgery and laparoscopy on different risk factors of postoperative complications in patients with colorectal cancer. Method： The clinical data of 96 patients with colorectal cancer who received surgical treatment in our hospital from January 2017 to January 2020 were retrospectively analyzed. According to different surgical methods， the patients were divided into group A and group B， with 48 patients in each group. Group A was treated with open surgery， while group B was treated with laparoscopy. The incidence of postoperative complications in the two groups was statistically analyzed， and risk factors leading to complications were also analyzed. Result： The total incidence of postoperative complications in group A was 47.92%， higher than 27.08% in group B， the incidence of postoperative infection and anastomotic leakage in group A were higher than those in group B， the differences were statistically significant (P<0.05). Multiple Logistic regression analysis showed that age， blood transfusion， blood loss， operation time and TNM stage of cancer were related factors for postoperative complications in group A (P<0.05)， while age， history of abdominal surgery， operation time and TNM stage of cancer were related factors for postoperative complications in group B (P<0.05). Conclusion： The incidence of postoperative complications in laparoscopic surgery is lower than that in open surgery， which can reduce postoperative complications due to age， blood loss， operation time and other factors. Strengthening preoperative evaluation of patients can greatly reduce postoperative complications.
[Key words] Open surgery Laparoscopic surgery Colorectal cancer Postoperative complications Risk factors
First-author’s address： Jiangning Hospital Affiliated to Nanjing Medical University， Nanjing 211100， China, 百拇医药(李圣平)
【关键词】 开放性手术 腹腔镜术 结直肠癌 术后并发症 风险因素
doi：10.14033/j.cnki.cfmr.2020.27.021 文献标识码 B 文章编号 1674-6805(2020)27-00-04
[Abstract] Objective： To investigate the influence of open surgery and laparoscopy on different risk factors of postoperative complications in patients with colorectal cancer. Method： The clinical data of 96 patients with colorectal cancer who received surgical treatment in our hospital from January 2017 to January 2020 were retrospectively analyzed. According to different surgical methods， the patients were divided into group A and group B， with 48 patients in each group. Group A was treated with open surgery， while group B was treated with laparoscopy. The incidence of postoperative complications in the two groups was statistically analyzed， and risk factors leading to complications were also analyzed. Result： The total incidence of postoperative complications in group A was 47.92%， higher than 27.08% in group B， the incidence of postoperative infection and anastomotic leakage in group A were higher than those in group B， the differences were statistically significant (P<0.05). Multiple Logistic regression analysis showed that age， blood transfusion， blood loss， operation time and TNM stage of cancer were related factors for postoperative complications in group A (P<0.05)， while age， history of abdominal surgery， operation time and TNM stage of cancer were related factors for postoperative complications in group B (P<0.05). Conclusion： The incidence of postoperative complications in laparoscopic surgery is lower than that in open surgery， which can reduce postoperative complications due to age， blood loss， operation time and other factors. Strengthening preoperative evaluation of patients can greatly reduce postoperative complications.
[Key words] Open surgery Laparoscopic surgery Colorectal cancer Postoperative complications Risk factors
First-author’s address： Jiangning Hospital Affiliated to Nanjing Medical University， Nanjing 211100， China, 百拇医药(李圣平)